Imai 2010 - Identification Compared with Pearl Robins and Principal Strata

Summary

Assumption 1 gives the same ACME expression as Pearl’s (2001) conditions, is easier to interpret, and needs no no-interaction assumption, but cannot condition on observed post-treatment confounders. Robins’ FRCISTG model can condition on them but then needs (no interaction). Petersen et al. weaken (4) at the cost of another assumption; Rubin’s principal strata define direct effects only for a latent subpopulation.

Overview

Section 3.3 compares Theorem 1 with five existing identification routes. The trade-off table below collects them.

Main Content

SourceAssumptionsPost-treatment confounders Extra assumptionRemark
This paper (Asm. 1)(4)-(5)not allowednoneany mediator type; any treatment regime
Pearl (2001, Thm 2)(6) $p(Y(t,m)X=x)p(M(t^*)X=x)Y_i(t,m)\perp M_i(t^*)X_i=x$
Robins (2003) FRCISTG(4) plus (8) $Y_i(t,m)\perp M_i(t)T_i=t,Z_i=z,X_i=x$allowed (observed)(9) with independent of (no interaction)
Petersen, Sinisi & van der Laan (2006)keep (5); replace (4) with (10) $Y_i(t,m)\perp T_iX_iM_i(t)\perp T_iX_i$not allowed
Hafeman & VanderWeele (2010)weaker set for binary --not shown to generalise to non-binary
Rubin (2004) principal stratadirect effect $E{Y(1,M(1))-Y(0,M(0))M(1)=M(0)}$--

Key trade-off. “Allowing for conditioning on observed post-treatment confounders requires an additional assumption for the identification of the ACME.”

Sobel (2008) (also Albert 2008; Jo 2008) uses an instrumental-variables approach to mediation in an LSEM but assumes the direct effect is zero for every unit a priori, which is undesirable when the natural direct effect is itself of interest.

Examples

Choosing an identification route for a marketing funnel

Treatment: a randomised geo-test of Meta spend. Mediator: branded-search clicks. Observed post-treatment confounder: e.g. a Google brand-campaign spend change triggered by the test. Asm. 1 would be violated (the post-treatment confounder is not conditioned on); Robins’ route allows conditioning on it but needs no spend-search interaction in the outcome. The analyst must pick which assumption is more defensible, or run the sensitivity analysis of Imai 2010 - Sensitivity Analysis with Error Correlation Rho on top.

Connections

See Also

Imai 2010 - Causal Mediation Analysis - Overview, Potential Outcomes Framework