Bareinboim Pearl 2016 - Causal Inference and Data Fusion - Overview

Summary

The paper unifies three classical biases under one structural-causal-model language and one inference method (do-calculus on a graph): confounding bias (tasks 1 and 2), sample selection bias (task 3) and transportability / cross-population bias (task 4). Each “design”, defined by the triple (population, regime, sampling method) of an available dataset, is a different syntactic form of data, and the strategy is always to transform the target query into an expression estimable from the datasets in hand. The authors claim complete graphical and algorithmic solutions for policy evaluation, transportability and data fusion in nonparametric DAG models.

Overview

Question. Given several heterogeneous datasets (different populations, observational vs experimental regimes, different sampling mechanisms), when and how can a causal effect in a target population be computed?

Thesis. “Not all data are created equal”: the design of each dataset must be encoded mathematically, and different designs support different inferences. Big data does not replace causal assumptions; it magnifies the need to reason about how data were acquired.

Contributions.

  1. A four-task taxonomy of generalization problems (Fig. 1).
  2. Statement of the two principles of causal inference (structural counterfactuals, structural independences) from which the rest follows.
  3. Review of identification results: backdoor, front-door, z-identification (auxiliary experiments) with the three do-calculus rules.
  4. The selection-backdoor criterion (Definition 4, Theorem 1) for recovering causal effects from sampling-biased data, and the clinical-trial generalization pattern (Eq. 14).
  5. Transport formulas (Eqs. 15-17), the complete decision procedure for transportability, and an assurance of completeness for multi-source data fusion (Summary Results 1-3).

Main Content

Source Map

Paper sectionPDF pagesContentCovered in
Abstract, Introduction: Causal Inference and Big Data, Fig. 11-2tasks 1-4, designs, outlinethis note, Bareinboim 2016 - SCM Principles and Confounding Bias (Fig. 1 table)
The Structural Causal Model; Two Principles2-3, Eq. 1 counterfactual, d-separation (Def. 1), Fig. 2ABareinboim 2016 - SCM Principles and Confounding Bias
Policy Evaluation and the Problem of Confounding3-5Eqs. 2-4, Def. 2, rules (Eqs. 5-7), backdoor (Def. 3, Eqs. 8-9), front-door (Eq. 10)Bareinboim 2016 - SCM Principles and Confounding Bias
Identification Through Auxiliary Experiments5-6z-identification, Fig. 3, Eqs. 11-12, Summary Result 1Bareinboim 2016 - SCM Principles and Confounding Bias
Sample Selection Bias6-7Fig. 4, Eq. 13, Def. 4 S-backdoor, Theorem 1Bareinboim 2016 - Sample Selection Bias and Recoverability
The Generalizability of Clinical Trials7Fig. 4F, Eq. 14, S-ignorability, Summary Result 2Bareinboim 2016 - Sample Selection Bias and Recoverability
Transportability and the Problem of Data Fusion7-8selection diagrams, Fig. 5, Eqs. 15-17, multi-population fusion, Summary Result 3Bareinboim 2016 - Transportability and Data Fusion
Conclusion8external validity “solved”, future workBareinboim 2016 - Transportability and Data Fusion
References 1-558bibliographycited inline

Key results at a glance

ProblemData availableResult
Confounding (task 1)backdoor adjustment ; front-door if no backdoor set
Auxiliary experiment (task 2), z-identifiable iff intercepts all directed paths and identifiable in
Selection bias (task 3) (+ population-level )S-backdoor admissible :
Transportability (task 4) in , observational in transport formula via selection diagram; e.g.

Examples

Three recoverability/transport designs in one table (details in the topic notes):

DesignQueryEstimand
Fig. 4B: , no confounding
Fig. 4F clinical trial, post-treatment (Eq. 14)
Fig. 5C biomarker (Eq. 17)

Connections

See Also